| 2007 |
| ALMA Awards |
Outstanding Actor - Motion Picture |
Nominated for Babel |
| Palm Springs International Film Festival |
Ensemble Performance Award |
Won for Babel |
| Screen Actors Guild Awards |
Outstanding Performance by a Cast in a Motion Picture |
Nominated for Babel |
| 2006 |
| BAFTA Awards |
Rising Star Award |
Nominated |
| Gotham Awards |
Best Ensemble Cast |
Won for Babel |
| 2005 |
| Spanish Actors Union |
Lead Performance, Male |
Nominated for Bad Education |
| Golden Satellite Awards |
Best Actor in a Motion Picture, Drama |
Nominated for Motorcycle Diaries |
| Premios ACE |
Best Actor |
Won for Motorcycle Diaries |
| Glitter Awards |
Best Actor |
Won for Bad Education |
| Cinema Writers Circle Awards, Spain |
Best Actor |
Nominated for Bad Education |
| Chlotrudis Awards |
Best Actor |
Won for Bad Education |
| BAFTA Awards |
Best Performance by an Actor in a Leading Role |
Nominated for Motorcycle Diaries |
| 2004 |
| Valdivia International Film Festival |
Best Actor |
Won for Bad Education |
| 2003 |
| Mexican Cinema Journalists |
Best Actor |
Won for The Crime of Padre Amaro |
| MTV Movie Awards, Mexico |
Favorite Actor |
Won for The Crime of Padre Amaro |
| MTV Movie Awards, Mexico |
Sexiest Scene |
Nominated with Ana Claudia Talancón for The Crime of Padre Amaro |
| Chlotrudis Awards |
Best Actor |
Won for Y tu mamá también |
| Chicago Film Critics Association Awards |
Most Promising Performer |
Nominated for Y tu mamá también and The Crime of Padre Amaro |
| Cannes Film Festival |
Chopard Trophy for Male Revelation |
Won |
| 2002 |
| Cinema Writers Circle Awards, Spain |
Best Supporting Actor |
Nominated for Don't Tempt Me |
| Goya Awards |
Best Supporting Actor |
Nominated for Don't Tempt Me |
| MTV Movie Awards, Latin America |
MTV North Feed (mostly Mexico) - Best Insult |
Won with Diego Luna for Y tu mamá también |
| MTV Movie Awards, Latin America |
MTV North Feed (mostly Mexico) - Best Kiss |
Nominated with Diego Luna for Y tu mamá también |
| MTV Movie Awards, Latin America |
MTV North Feed (mostly Mexico) - Best Kiss |
Won with Maribel Verdú for Y tu mamá también |
| 2001 |
| Valdivia International Film Festival |
Best Actor |
Won with Diego Luna for Y tu mamá también |
| Ariel Awards, Mexico |
Silver Ariel for Best Actor |
Won for Amores Perros |
| 2000 |
| Chicago International Film Festival |
Silver Hugo for Best Actor |
Won for Amores Perros; Tied with Emilio Echevarría for Amores Perros |
